noninvasive methods to evaluate liver fibrosis in chronic hcv infection

Noninvasive Methods to Evaluate Liver Fibrosis in Chronic HCV Infection

Sirli et al.'s (1) effort to compare several noninvasive methods of fibrosis assessment in chronic hepatitis C virus (HCV) infection is commendable. Their study evaluated several simple serological tests for the prediction of fibrosis in chronic HCV infection: number of platelets, the aspartate aminotransferase–platelet ratio index (APRI test), the Forns score, the Lok score, and the FIB-4 scor...

Endothelial Dysfunction Correlates with Liver Fibrosis in Chronic HCV Infection

Background. Hepatitis C virus (HCV) infection can exert proatherogenic activities due to its direct action on vessel walls and/or via the chronic inflammatory process involving the liver. Aims. To clarify the role of HCV in atherosclerosis development in monoinfected HCV patients at different degrees of liver fibrosis and with no risk factors for coronary artery disease. Methods. Forty-five pat...

A Comparative Study of Non-Invasive Methods for Fibrosis Assessment in Chronic HCV Infection

BACKGROUND AND AIMS To compare several non-invasive methods of fibrosis assessment in chronic hepatitis C virus (HCV) infection (platelet count, the APRI score, the Forns score, the Lok score, FIB-4, Transient Elastography [TE]), versus percutaneous liver biopsy (LB). METHODS Our study included 150 patients with chronic HCV infection in which LB, liver stiffness measurement (LSM) by means of ...

Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy

OBJECTIVES To evaluate the diagnostic performance of seven non-invasive tests (NITs) of liver fibrosis and to assess fibrosis progression over time in HIV/HCV co-infected patients. METHODS Transient elastography (TE) and six blood tests were compared to histopathological fibrosis stage (METAVIR). Participants were followed over three years with NITs at yearly intervals. RESULTS Area under t...

noninvasive evaluation of liver fibrosis in patients with chronic hepatitis c

liver fibrosis and noninvasive serum based biomarkers

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